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methotrexate-loaded spherical polymeric nanoconstructs

Based on

1 Articles
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

lipid mixture

Type Complex Compound
Formula
Role layer
3

methotrexate

abitrexate folex MTX
Type Single Compound
Formula C20H22N8O5
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
ApoE -/- (KO) male mouse with high-fat diet-induced atherosclerosis

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)
  1. bpVIrlOBaFsW
Product

methotrexate-loaded spherical polymeric nanoconstructs

Hydrodynamic diameter: 84.0 - 87.0 nm

Size: ~ 100 nm

Medium/Support: none

References

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