Loading ...

siRNA-loaded poly(2-methacryloyloxyethyl phosphorylcholine)-b-poly(dimethylamino ethyl methacrylate-co-butyl methacrylate) polyplexes

Based on

1 Articles
2017 Most recent source

Composition

1

poly(2-methacryloyloxyethyl phosphorylcholine)-b-poly(dimethylamino ethyl methacrylate-co-butyl methacrylate)

PMPC-b-P(DMAEMA-co-BMA)
Type Polymer
Formula
Role carriers
2

small interfering RNA

siRNa
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
zeta potential

More information available to subscribers only.

Or, view sample content

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

More information/entries available to subscribers only.

Or, view sample content

Biological effects

Biological system Test details Nanomaterial Variant Source
CD-1 mouse

More information/entries available to subscribers only.

Or, view sample content

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(2-methacryloyloxyethyl phosphorylcholine)-b-poly(dimethylamino ethyl methacrylate-co-butyl methacrylate)
  • small interfering RNA
  1. yikv0mRDQ1foic
  2. SkjA
Product

siRNA-loaded poly(2-methacryloyloxyethyl phosphorylcholine)-b-poly(dimethylamino ethyl methacrylate-co-butyl methacrylate) polyplexes

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • poly(2-methacryloyloxyethyl phosphorylcholine)-b-poly(dimethylamino ethyl methacrylate-co-butyl methacrylate)
  • Cy5-labeled small interfering RNA
  1. O8HjemGWZH6QZf
  2. vSbG
Product

siRNA-loaded poly(2-methacryloyloxyethyl phosphorylcholine)-b-poly(dimethylamino ethyl methacrylate-co-butyl methacrylate) polyplexes

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Product

siRNA-loaded poly(2-methacryloyloxyethyl phosphorylcholine)-b-poly(dimethylamino ethyl methacrylate-co-butyl methacrylate) polyplexes

Size: not specified

Medium: NaCl solution

Support: none

Method 4

Type: Physical formation
Source:
Product

siRNA-loaded poly(2-methacryloyloxyethyl phosphorylcholine)-b-poly(dimethylamino ethyl methacrylate-co-butyl methacrylate) polyplexes

Hydrodynamic diameter: 86.58 - 203.02 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Product

siRNA-loaded poly(2-methacryloyloxyethyl phosphorylcholine)-b-poly(dimethylamino ethyl methacrylate-co-butyl methacrylate) polyplexes

Size: not specified

Medium: NaCl solution

Support: none

References

Full content is available to subscribers only

To view content please choose from the following:


Sign up for a free trial