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[64Cu]-labeled amphiphilic perylene diimide derivatives nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

1

amphiphilic perylene diimide derivatives nanoparticles

PDI NP
Type Nano Material
Formula
Role core
2

1,4,7,10-tetraazacyclododecane-N,-N',N'',N'''-tetraacetic acid

1,4,7,10- tetraazacyclododecane-1,4,7,10-tetraacetic acid 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid tetraazacyclododecane-1,4,7,10-tetraacetic acid cyclododecane DOTA CCD
Type Single Compound
Formula C16H28N4O8
Role layer
3

64copper isotope

64Cu isotope copper-64 copper 64Cu
Type Single Compound
Formula 64Cu
Role loaded material

Applications

Area Application Nanomaterial Variant Source
diagnostics

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Biological effects

Biological system Test details Nanomaterial Variant Source
female FVB mouse xenografted with human glioblastoma U87MG cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • 1,4,7,10-tetraazacyclododecane-N,-N',N'',N'''-tetraacetic acid
  1. 20tMlmfUv6Fpcyde
  2. Bin
  3. J5F
Product

[64Cu]-labeled amphiphilic perylene diimide derivatives nanoparticles

Hydrodynamic diameter: 92.2 - 119.0 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • 1,4,7,10-tetraazacyclododecane-N,-N',N'',N'''-tetraacetic acid
  1. hQIBfz9ZceEAJ2OF
  2. Ga7
  3. J6X
Product

[64Cu]-labeled amphiphilic perylene diimide derivatives nanoparticles

Hydrodynamic diameter: 57.7 - 66.9 nm

Medium/Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • 1,4,7,10-tetraazacyclododecane-N,-N',N'',N'''-tetraacetic acid
  1. E7VDCgIX5BGr0eXH
  2. g9w
  3. RdJ
Product

[64Cu]-labeled amphiphilic perylene diimide derivatives nanoparticles

Hydrodynamic diameter: 28.1 - 34.5 nm

Medium/Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • 1,4,7,10-tetraazacyclododecane-N,-N',N'',N'''-tetraacetic acid
  1. mRDZrMZmzYcIkI18
  2. d0l
  3. 6um
Product

[64Cu]-labeled amphiphilic perylene diimide derivatives nanoparticles

Hydrodynamic diameter: 176.5 - 213.7 nm

Medium/Support: none

References

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