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IR780-loaded poly(ε-caprolactone)-b-poly(ethyl ethylene phosphate-co-methyl ethylene phosphate)/TAT peptide-functionalized poly(ethylene glycol)-b-poly(ε-caprolactone) polymeric micelles

Based on

2 Articles
2018 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

dextran/poloxamer 407 nanoparticles

Type Nano Material
Formula
Role carriers
2

near-infrared dye IR780 iodide

IR-780 iodide NIR dye IR780 IR780 iodide IR780 dye IR-780 IR780
Type Single Compound
Formula C36H44ClIN2
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability in serum

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
fluorescence spectroscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
Alexa Fluor 594-conjugated ovalbumin

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(ε-caprolactone)-b-poly(ethyl ethylene phosphate-co-methyl ethylene phosphate)
  • TAT peptide-functionalized poly(ethylene glycol)-b-poly(ε-caprolactone)
  • near-infrared dye IR780 iodide
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Product

IR780-loaded poly(ε-caprolactone)-b-poly(ethyl ethylene phosphate-co-methyl ethylene phosphate)/TAT peptide-functionalized poly(ethylene glycol)-b-poly(ε-caprolactone) polymeric micelles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • poly(ε-caprolactone)-b-poly(ethyl ethylene phosphate-co-methyl ethylene phosphate)
  • TAT peptide-functionalized poly(ethylene glycol)-b-poly(ε-caprolactone)
  • near-infrared dye IR780 iodide
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Product

IR780-loaded poly(ε-caprolactone)-b-poly(ethyl ethylene phosphate-co-methyl ethylene phosphate)/TAT peptide-functionalized poly(ethylene glycol)-b-poly(ε-caprolactone) polymeric micelles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • poly(ε-caprolactone)-b-poly(ethyl ethylene phosphate-co-methyl ethylene phosphate)
  • TAT peptide-functionalized poly(ethylene glycol)-b-poly(ε-caprolactone)
  • near-infrared dye IR780 iodide
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Product

IR780-loaded poly(ε-caprolactone)-b-poly(ethyl ethylene phosphate-co-methyl ethylene phosphate)/TAT peptide-functionalized poly(ethylene glycol)-b-poly(ε-caprolactone) polymeric micelles

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • oxidation-sensitive dextran
  • near-infrared dye IR780 iodide
  • Pluronic® F-127
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Product

IR780-loaded poly(ε-caprolactone)-b-poly(ethyl ethylene phosphate-co-methyl ethylene phosphate)/TAT peptide-functionalized poly(ethylene glycol)-b-poly(ε-caprolactone) polymeric micelles

Size: 120 - 180 nm

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • oxidation-sensitive dextran
  • near-infrared dye IR780 iodide
  • acetalated dextran
See all (4)
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Product

IR780-loaded poly(ε-caprolactone)-b-poly(ethyl ethylene phosphate-co-methyl ethylene phosphate)/TAT peptide-functionalized poly(ethylene glycol)-b-poly(ε-caprolactone) polymeric micelles

Size: 160 - 240 nm

Medium/Support: none

References

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