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RNA-loaded apolipoprotein E3-modified lipid-encapsulated CaP nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

1

calcium orthophosphate

β-tricalcium phosphate tricalcium phosphate calcium phosphate β-TCP CaPh CaP TCP CP
Type Single Compound
Formula Ca3(PO4)2
Role core
2

dioleoylphosphatydic acid

dioleoylphosphatydic acid DOPA
Type Single Compound
Formula C39H73O8P
Role layer
3

1,2-dimyristoyl-sn-glycero-3-phosphocholine

DMPC
Type Single Compound
Formula C36H73NO8P
Role layer
4

apolipoprotein E3

ApoE3
Type Biomolecule
Formula
Role layer
5

double-stranded RNA

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human glioblastoma initiating cells

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Preparation

Method 1

Type: Physical formation
Source:
  1. 4LZQv1Q
Product

RNA-loaded apolipoprotein E3-modified lipid-encapsulated CaP nanoparticles

Hydrodynamic diameter: 25.38 - 32.90 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  1. Fj5p8DQ
Product

RNA-loaded apolipoprotein E3-modified lipid-encapsulated CaP nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  1. IGsS7ok
Product

RNA-loaded apolipoprotein E3-modified lipid-encapsulated CaP nanoparticles

Diameter: ~ 20 nm

Hydrodynamic diameter: 13.07 - 32.27 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
  1. KcBCmwZ
Product

RNA-loaded apolipoprotein E3-modified lipid-encapsulated CaP nanoparticles

Hydrodynamic diameter: 21.65 - 34.45 nm

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  1. vlFoblq
Product

RNA-loaded apolipoprotein E3-modified lipid-encapsulated CaP nanoparticles

Size: not specified

Medium/Support: none

References

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