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siRNA/supercharged coiled-coil protein-complexed DOTAP:sodium cholate liposomes

Based on

1 Articles
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

DOTAP:sodium cholate liposomes

Type Nano Material
Formula
Role core
2

supercharged coiled-coil protein

Type Biomolecule
Formula
Role layer
3

Keap1 mRNA-targeting siRNA

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
diabetic Leprdb/db mouse with cutaneous wound

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Preparation

Method 1

Type: Physical formation
Source:
Product

siRNA/supercharged coiled-coil protein-complexed DOTAP:sodium cholate liposomes

Hydrodynamic diameter: 192.85 - 213.15 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • supercharged coiled-coil protein
  • Keap1 mRNA-targeting siRNA
  1. vutZq44hMOTwST
Product

siRNA/supercharged coiled-coil protein-complexed DOTAP:sodium cholate liposomes

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • supercharged coiled-coil protein
  • Keap1 mRNA-targeting siRNA
  1. VBL6xln3n5hD90
Product

siRNA/supercharged coiled-coil protein-complexed DOTAP:sodium cholate liposomes

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • supercharged coiled-coil protein
  • Keap1 mRNA-targeting siRNA
  1. qHzDuTTknMMXUf
Product

siRNA/supercharged coiled-coil protein-complexed DOTAP:sodium cholate liposomes

Hydrodynamic diameter: 282.92 - 538.42 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • supercharged coiled-coil protein
  • Keap1 mRNA-targeting siRNA
  1. ITki5jvsRJ6DBI
Product

siRNA/supercharged coiled-coil protein-complexed DOTAP:sodium cholate liposomes

Size: not specified

Medium/Support: none

References

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