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siRNA-loaded doxorubicin-loaded β-cyclodextrin-grafted PEI-coated doxorubicin-coated 3-isocyanatopropyltriethoxysilane-modified mesoporous silica nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

1

doxorubicin-loaded β-cyclodextrin-grafted PEI-coated doxorubicin-coated 3-isocyanatopropyltriethoxysilane-modified mesoporous silica nanoparticles

CP-MSNP@DOX
Type Nano Material
Formula
Role carriers
2

FAM-labeled siRNA

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
confocal laser scanning microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
athymic nude mouse bearing human breast tumor (MDA-MB-231) xenograft

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Preparation

Method 1

Type: Physical formation
Source:
  1. 0JDTcY4cJ9STxQ3f0du07IDO1ASFV7QRO5hqwr47aUK9Zk0H5taQVKe8pl
  2. vw4mNvx
Product

siRNA-loaded doxorubicin-loaded β-cyclodextrin-grafted PEI-coated doxorubicin-coated 3-isocyanatopropyltriethoxysilane-modified mesoporous silica nanoparticles

Hydrodynamic diameter: 96.78 - 105.22 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
  1. YgqsGYZkQc8SSefWqbXcaflm26Jn51yJtmb6ky3iH53eZc1nDr6hcwQiG7
  2. Qx1Hh2z
Product

siRNA-loaded doxorubicin-loaded β-cyclodextrin-grafted PEI-coated doxorubicin-coated 3-isocyanatopropyltriethoxysilane-modified mesoporous silica nanoparticles

Size: not specified

Medium/Support: none

References

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