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sorafenib/spermine-functionalized acetalated dextran core-shell nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

1

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide

sorafenib SFN SOR SF
Type Single Compound
Formula C21H16ClF3N4O3
Role core
2

spermine-functionalized acetalated dextran

Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
isoelectric point

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
breast cancer MDA-MB-231 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
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  2. qgB7VvYIcXkRQ2ZgL3usKSCtOQ5OAaUrImjDNjhiKlDawsvdLm1xbTbinDO5
Product

sorafenib/spermine-functionalized acetalated dextran core-shell nanoparticles

Diameter: ~ 175 - ~ 230 nm

Diameter: ~ 220 - ~ 280 nm

Medium/Support: none

References

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