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SFN nanocrystals

Based on

2 Articles
2017 Most recent source

Composition

1

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide

sorafenib SFN SOR SF
Type Single Compound
Formula C21H16ClF3N4O3
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on ph

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Characterization

Method Nanomaterial Variant Source
differential scanning calorimetry

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Biological effects

Biological system Test details Nanomaterial Variant Source
breast cancer MDA-MB-231 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  1. z0OZuDwxAJy7IWmR8Q
  2. xlQUTYXvj9Hb3jmj4zEk53rZz50F9e96AyscWxaObHpDs845sJoy6bWOHsX3
Product

SFN nanocrystals

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  1. ipM7lWR
  2. MNjiE
Product

SFN nanocrystals

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  1. FkRNCfysIAj8wRb7Je
  2. q4cttWMCxGDJTt9Oy8JwmWTOo7GKmmil71KXWN6AB2AOFVjdpGSqqSRZCvTc
Product

SFN nanocrystals

Hydrodynamic diameter: ~ 149 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  1. v5DWxH1OBajRAFdFCx
  2. wpFmScGRcI56P8LnUvIj5Jmax55chDBniRlhUNsrowQ1hTUOxtgv5xYRsT3F
Product

SFN nanocrystals

Hydrodynamic diameter: ~ 169 nm

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  1. Samj571F53DcRnO1wi
  2. SMj4hFyRrbblKEBgB1KomD3qnAMtzcWsD2OL3kiRpPtjX5jU6SNaNdUr46uA
Product

SFN nanocrystals

Hydrodynamic diameter: ~ 250 nm

Medium/Support: none

References

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