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Cas9 mRNA/single guideRNA against LoxP-loaded zwitterionic amino lipid nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

zwitterionic amino lipid nanoparticles

ZAL nanoparticles ZAL NP ZNP
Type Nano Material
Formula
Role carriers
2

Cas9 protein encoding mCherry-labeled RNA

Cas9 mRNA
Type Biomolecule
Formula
Role loaded material
3

single guide RNA against LoxP

sgLoxP
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
Rosa 26-LSL-tdTomato mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • Cas9 protein encoding mCherry-labeled RNA
  • cholesterol
  • single guide RNA against LoxP
See all (5)
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  3. dwQLzMo1iP1
Product

Cas9 mRNA/single guideRNA against LoxP-loaded zwitterionic amino lipid nanoparticles

Hydrodynamic diameter: ~ 90 - ~ 115 nm

Medium: phosphate buffer solution

Support: none

References

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