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RGD-modified dendrimer-stabilized-coated gold nanostars

Based on

1 Articles
2016 Most recent source

Composition

1

PAMAM dendrimer G3-stabilized-coated gold nanostars

Au DSNS
Type Nano Material
Formula
Role core
2

6-maleimidohexanoate-modified carboxylated poly(ethylene glycol)

6-maleimidohexanoate-PEG-COOH
Type Polymer
Formula
Role layer
3

thiolated cyclic RGD peptide

Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human glioblastoma U87MG cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • (2S)-2-{2-[(2S)-2-amino-5-carbamimidamidopentanamido]acetamido}butanedioic acid
  • 6-maleimidohexanoate-modified carboxylated poly(ethylene glycol)
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  2. 6IgP7bwa
Product

RGD-modified dendrimer-stabilized-coated gold nanostars

Diameter: 42.5 - 67.7 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

RGD-modified dendrimer-stabilized-coated gold nanostars

Hydrodynamic diameter: ~ 690 nm

Medium: Dulbecco's modified Eagle medium

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
Product

RGD-modified dendrimer-stabilized-coated gold nanostars

Hydrodynamic diameter: ~ 660 nm

Medium: phosphate buffer solution

Support: none

Method 4

Type: Physical formation
Source:
Product

RGD-modified dendrimer-stabilized-coated gold nanostars

Hydrodynamic diameter: ~ 660 nm

Medium: water

Support: none

References

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