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gold nanoparticles/apolipoprotein A1/1,2-dioleoyl-sn-glycero-3-phosphocholine:1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[3-(2-pyridyldithio)propionate]/cholesterol/1,2-dioleoyl-3-trimethylammonium-propane/siRNA

Based on

1 Articles
2016 Most recent source

Composition

1

RNA

Type Biomolecule
Formula
Role core
2

N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecenoyloxy]-1-propanaminium

(N-[1-(2, 3-dioleoyloxy)propyl]-N,N,N-trimethylammoniumsalt) 1,2-di(9Z-octadecenoyloxy)-3-trimethylammonium-propane N-(1-(2,3-dioleoyloxy)propyl)-N,N,N-trimethylammonium N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium 1,2-di-(9Z-octadecenoyl)-3-trimethylammonium-propane 1,2-dioleoyloxy-3-trimethylammonium-propane 1, 2-dioleoyl-3-trimethylammonium propane 1,2-dioleoyl-3-(trimethylammonium)propane 1,2-dioleoyl-3-trimethyl-ammonium-propane 1,2-dioleoyl-3-trimethylammonium propane 1,2-dioleoyl-3-trimethylammonium-propane 1,2-dioleoyl-3-trimethylammonium-propan 1,2-dioleoyl-3-trimethylammoniumpropane DOTAP
Type Single Compound
Formula C42H80NO4
Role loaded material
3

gold nanoparticles/apolipoprotein A1/1,2-dioleoyl-sn-glycero-3-phosphocholine:1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[3-(2-pyridyldithio)propionate]/cholesterol

Au NP/apo A-I/DOPC/PDP-PE/cholesterol
Type Nano Material
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
human breast cancer (MDA-MB-231) cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • RNA
  1. tLRjYjPNEkNPhJ5M
Product

gold nanoparticles/apolipoprotein A1/1,2-dioleoyl-sn-glycero-3-phosphocholine:1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[3-(2-pyridyldithio)propionate]/cholesterol/1,2-dioleoyl-3-trimethylammonium-propane/siRNA

Size: not specified

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • RNA
  1. 8TdK3KDYGZBkjIth
Product

gold nanoparticles/apolipoprotein A1/1,2-dioleoyl-sn-glycero-3-phosphocholine:1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[3-(2-pyridyldithio)propionate]/cholesterol/1,2-dioleoyl-3-trimethylammonium-propane/siRNA

Size: not specified

Medium/Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • RNA
  1. qTiYrj928PtBPAxg
Product

gold nanoparticles/apolipoprotein A1/1,2-dioleoyl-sn-glycero-3-phosphocholine:1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[3-(2-pyridyldithio)propionate]/cholesterol/1,2-dioleoyl-3-trimethylammonium-propane/siRNA

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Product

gold nanoparticles/apolipoprotein A1/1,2-dioleoyl-sn-glycero-3-phosphocholine:1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[3-(2-pyridyldithio)propionate]/cholesterol/1,2-dioleoyl-3-trimethylammonium-propane/siRNA

Hydrodynamic diameter: ~ 70 nm

Size: 93.00 - 147.00 nm

Medium: water

Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • RNA
  1. uBlVgXixDF9xtdek
Product

gold nanoparticles/apolipoprotein A1/1,2-dioleoyl-sn-glycero-3-phosphocholine:1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[3-(2-pyridyldithio)propionate]/cholesterol/1,2-dioleoyl-3-trimethylammonium-propane/siRNA

Size: 93.00 - 147.00 nm

Medium/Support: none

References

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