Loading ...

lopinavir-loaded polymer nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

polyvinyl alcohol-polyethylene glycol graft-copolymer

Kollicoat
Type Polymer
Formula
Role core
2

3α,12α-dihydroxy-5β-cholanic acid sodium salt

sodium deoxycholate NaDOC NDC DOC SDC DC SD
Type Single Compound
Formula C24H39NaO4
Role layer
3

[1S-[1R*,(R*),3R*,4R*]]-N-[4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenyl-methyl)pentyl]tetrahydro-a-(1-methyl-ethyl)-2-oxo-1-(2H)-pyrimidineacetamide

lopinavir LPV
Type Single Compound
Formula C37H48N4O5
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

More information available to subscribers only.

Or, view sample content

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

More information available to subscribers only.

Or, view sample content

Biological effects

Biological system Test details Nanomaterial Variant Source
Caco-2 cells

More information available to subscribers only.

Or, view sample content

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • polyvinyl alcohol-polyethylene glycol graft-copolymer
  • 3α,12α-dihydroxy-5β-cholanic acid sodium salt
  • [1S-[1R*,(R*),3R*,4R*]]-N-[4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenyl-methyl)pentyl]tetrahydro-a-(1-methyl-ethyl)-2-oxo-1-(2H)-pyrimidineacetamide
  1. 7nfXmWR32X
  2. QgoEh
Product

lopinavir-loaded polymer nanoparticles

Hydrodynamic diameter: 521 - 557 nm

Medium: water

Support: none

References

Full content is available to subscribers only

To view content please choose from the following:


Sign up for a free trial