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anti-PLK-1 siRNA-loaded GDDC4 nanomicelles

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

PCB-P(DPAx-co-DMAEMAy)-PG nanomicelles

GDDC4 nanomicelles GDDC4-M GDDC-M
Type Nano Material
Formula
Role carriers
2

anti-PLK-1 small interfering RNA

anti-PLK-1 siRNA
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
genetic engineering

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Biological effects

Biological system Test details Nanomaterial Variant Source
293A cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • anti-PLK-1 small interfering RNA
  • poly(carboxybetaine)-poly(dimethylaminoethyl methacrylate-co-diisopropylethyl methacrylate)-guanidinated poly(aminoethyl methacrylate) triblock polycation
  1. cDFjecMH0vpyGZEf0AsTmM6c3wrMvHrLRSTuf81
Product

anti-PLK-1 siRNA-loaded GDDC4 nanomicelles

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • anti-PLK-1 small interfering RNA
  • poly(carboxybetaine)-poly(dimethylaminoethyl methacrylate-co-diisopropylethyl methacrylate)-guanidinated poly(aminoethyl methacrylate) triblock polycation
  1. Xd6Ol4cROyP9agja9MKx9k0OC9WyPR55yvmtYgn
Product

anti-PLK-1 siRNA-loaded GDDC4 nanomicelles

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • anti-PLK-1 small interfering RNA
  • poly(carboxybetaine)-poly(dimethylaminoethyl methacrylate-co-diisopropylethyl methacrylate)-guanidinated poly(aminoethyl methacrylate) triblock polycation
  1. 2FJigFfvQqYQN40uozUi4yeb70Lsd8PwvQpODVL
Product

anti-PLK-1 siRNA-loaded GDDC4 nanomicelles

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • anti-PLK-1 small interfering RNA
  • poly(carboxybetaine)-poly(dimethylaminoethyl methacrylate-co-diisopropylethyl methacrylate)-guanidinated poly(aminoethyl methacrylate) triblock polycation
  1. Fy3OcFu1pXJ3KQqsjjn6dhavKC8qaKHkuoQvluD
Product

anti-PLK-1 siRNA-loaded GDDC4 nanomicelles

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • anti-PLK-1 small interfering RNA
  • poly(carboxybetaine)-poly(dimethylaminoethyl methacrylate-co-diisopropylethyl methacrylate)-guanidinated poly(aminoethyl methacrylate) triblock polycation
  1. M0tRWVlbAdbM6rjdswtoLCvSyxWZMKbHHCLn64M
Product

anti-PLK-1 siRNA-loaded GDDC4 nanomicelles

Size: not specified

Medium: phosphate buffer solution

Support: none

References

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