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mTP/REV-conjugated peptidylprolyl isomerase B small interfering RNA-loaded porous silicon-calcium silicate core-shell nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

porous silicon nanoparticles

pSiNP
Type Nano Material
Formula
Role core
2

calcium silicate

Type Single Compound
Formula CaSiO3
Role layer
3

peptidylprolyl isomerase B small interfering RNA

siPPIB
Type Complex Compound
Formula
Role loaded material
4

(3-aminopropyl)-dimethyl-ethoxysilane moiety

(3-aminopropyl)methoxydimethylsilane moiety (3-aminopropyl)dimethylethoxysilane moiety 3-(aminopropyl)dimethylethoxysilane moiety 3-aminoproplyldimethylethoxysilane moiety 3-aminopropyldimethylmethoxysilane moiety 3-aminopropyldimethylethoxysilane moiety aminopropyldimethylmethoxysilane moiety 3-aminoproplyldimethylsilane moiety 3-aminopropyldimethylsiloxy group APDMES moiety APDMS moiety APMS moiety
Type Single Compound
Formula -C5H14NOSi
Role graft
5

polyethylene glycol linker

Type Complex Compound
Formula
Role layer
6

mTP

Type Biomolecule
Formula
Role layer
7

5-carboxyfluorescein-terminated REV

Type Biomolecule
Formula
Role layer

Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
brain-injured mouse

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Preparation

Method 1

Type: Physical formation
Source:
  1. qf5L7
  2. EjP2qP2
  3. oF7x
  4. Zn4
Product

mTP/REV-conjugated peptidylprolyl isomerase B small interfering RNA-loaded porous silicon-calcium silicate core-shell nanoparticles

Hydrodynamic diameter: 220 nm

Medium: ethanol

Support: none

References

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