Loading ...

ICG/doxorubicin-loaded PEG-peptide-modified mesoporous silica nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

silicon dioxide

silicic oxide silica
Type Single Compound
Formula SiO2
Role core
2

PEG-silane

Type Polymer
Formula
Role layer
3

(3-aminopropyl)trimethoxysilane moiety

(3-aminopropyl)trimethoxysilane moiety (3-aminopropyl)triethoxysilane moiety γ-aminopropyltriethoxy silane moiety 3-aminopropyltrimethoxysilane moiety γ-aminopropyltriethoxysilane moiety 3-aminopropyltriethoxysilane moiety (3-aminopropyl)trioxysilane moiety (3-aminopropyl)silanetrioxy group 3-aminopropylsilanetrioxy group 3-aminopropylsiloxy fragment 3-aminopropyl silane moiety 3-aminopropylsilane moiety γ-APTES moiety 3-APTS moiety APTES moiety APTMS moiety AMPS moiety APTS moiety APS moiety
Type Single Compound
Formula -C3H8NO3Si-
Role layer
4

azobis[N-(2-carboxyethyl)-2-methylpropionamidine]

Type Single Compound
Formula C14H26N6O4
Role layer
5

.6- monodeoxy-(2-aminoethylamino)-β-cyclodextrin

mono-6-deoxy-6-ethylenediamine-β-cyclodextrin ethylenediamino modified-β-cyclodextrin mono-6-ethylenediamine-β-cyclodextrin mono-6-ethylenediamine-β-CD mono-6-deoxy-6-EDA-β-CD β-cyclodextrin moiety amino-β-cyclodextrin β-cyclodextrin-NH2 NH2-β-CD β-CD-NH2 EDA-β-CD
Type Single Compound
Formula C44H76N2O34
Role layer
6

RGD motif-containing peptide

PEG-peptide
Type Biomolecule
Formula
Role layer
7

sodium 4-[2-[(1E,3E,5E,7Z)-7-[1,1-dimethyl-3-(4-sulfonatobutyl)benzo[e]indol-2-ylidene]hepta-1,3,5-trienyl]-1,1-dimethylbenzo[e]indol-3-ium-3-yl]butane-1-sulfonate

3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide Iindocyanine Green Indocyanine Green indocyanine green IC-Green® ICG IGG IcG
Type Single Compound
Formula C43H47N2NaO6S2
Role loaded material
8

doxorubicin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
doxorubicin release dependent on irradiation

More information/entries available to subscribers only.

Or, view sample content

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

More information available to subscribers only.

Or, view sample content

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

More information/entries available to subscribers only.

Or, view sample content

Biological effects

Biological system Test details Nanomaterial Variant Source
4T1 tumor-bearing female BALB/c mouse

More information/entries available to subscribers only.

Or, view sample content

Preparation

Method 1

Type: Chemical synthesis
Source:
  1. KN9kILws7skRcLwPHb9NTDW64RI
Product

ICG/doxorubicin-loaded PEG-peptide-modified mesoporous silica nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
  1. ST1BeEINWJkrcYoskd9HPDLQYkt
Product

ICG/doxorubicin-loaded PEG-peptide-modified mesoporous silica nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Product

ICG/doxorubicin-loaded PEG-peptide-modified mesoporous silica nanoparticles

Hydrodynamic diameter: 79.4 - 84.2 nm

Medium: water

Support: none

References

Full content is available to subscribers only

To view content please choose from the following:

We use cookies to improve your experience with our site. More information

Sign up for a free trial