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doxorubicin-nitroveratryl derivative-linked 7-azidoheptanoic acid-functionalized maleimide-functionalized methoxypolyethylene glycol-functionalized Qβ VLP nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

Qβ virus-like particles

Qβ VLP nanoparticles Qβ VLP
Type Nano Material
Formula
Role core
2

maleimide-functionalized methoxypolyethylene glycol

maleimide-functionalized mPEG
Type Polymer
Formula
Role layer
3

-C50H60N6O19

Type Single Compound
Formula -C50H60N6O19
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability dependent on cell culture presence

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
breast cancer cell line MCF-7

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Preparation

Method 1

Type: Physical formation
Source:
Product

doxorubicin-nitroveratryl derivative-linked 7-azidoheptanoic acid-functionalized maleimide-functionalized methoxypolyethylene glycol-functionalized Qβ VLP nanoparticles

Diameter: 19.6 - 32.6 nm

Medium: water

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • C10H14N4O4
  1. r07c9euk1yU0ldGtsp0EZaB0E
Product

doxorubicin-nitroveratryl derivative-linked 7-azidoheptanoic acid-functionalized maleimide-functionalized methoxypolyethylene glycol-functionalized Qβ VLP nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • C10H14N4O4
  1. vhHFtkuQn3Fn5zf3XKQ07tD8W
Product

doxorubicin-nitroveratryl derivative-linked 7-azidoheptanoic acid-functionalized maleimide-functionalized methoxypolyethylene glycol-functionalized Qβ VLP nanoparticles

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Product

doxorubicin-nitroveratryl derivative-linked 7-azidoheptanoic acid-functionalized maleimide-functionalized methoxypolyethylene glycol-functionalized Qβ VLP nanoparticles

Diameter: 29.1 - 40.1 nm

Medium: water

Support: none

References

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