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1,2-dimyristoyl-sn-glycero-3-phosphocholine styrene/maleic acid copolymer/lipid particles

Based on

1 Articles
2016 Most recent source

Composition

1

(2R)-2,3-bis(tetradecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate

1,2-dimyristoyl-sn-glycero-3-phosphocholine dimyristoyl-2-hydroxy-sn-glycero-3-phosphocholine 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine 1,2-dinonadecanoyl-sn-glycero-3-phosphocholine 1,2-dimyristoyl-sn-glycero-3- phosphocholine 1,2-dimyristoyl-sn-glycero-3-phosphocholine 2-dimyristoyl-sn-glycero-3-phosphocholine dimyristoyl-sn-glycero-3-phosphocholine L-α-dimyristoylphosphatidylcholine dimyristoyl phosphatidylcholine dimyristoylphosphatidylcholine di-14:0PC DMPC DMPE
Type Single Compound
Formula C36H72NO8P
Role core
2

copolymer of styrene and maleic acid

styrene/maleic acid copolymer Xiran SL25010 S25 SMA
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability in presence of dmpc large unilamellar vesicles

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • Tris buffer
  • (2R)-2,3-bis(tetradecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
Product

1,2-dimyristoyl-sn-glycero-3-phosphocholine styrene/maleic acid copolymer/lipid particles

Hydrodynamic diameter: ~ 15 nm

Medium: Tris buffer

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • Tris buffer
  • (2R)-2,3-bis(tetradecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
Product

1,2-dimyristoyl-sn-glycero-3-phosphocholine styrene/maleic acid copolymer/lipid particles

Hydrodynamic diameter: ~ 23 nm

Medium: Tris buffer

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • Tris buffer
  • (2R)-2,3-bis(tetradecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
Product

1,2-dimyristoyl-sn-glycero-3-phosphocholine styrene/maleic acid copolymer/lipid particles

Hydrodynamic diameter: ~ 14 nm

Medium: Tris buffer

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • Tris buffer
  • (2R)-2,3-bis(tetradecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
Product

1,2-dimyristoyl-sn-glycero-3-phosphocholine styrene/maleic acid copolymer/lipid particles

Hydrodynamic diameter: ~ 13 nm

Medium: Tris buffer

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • Tris buffer
  • (2R)-2,3-bis(tetradecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
Product

1,2-dimyristoyl-sn-glycero-3-phosphocholine styrene/maleic acid copolymer/lipid particles

Hydrodynamic diameter: ~ 36 nm

Medium: Tris buffer

Support: none

References

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