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mRNA-loaded modified dendrimer nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

2-tridecyloxirane-modified poly(amido amine) dendrimer generation 1

2-tridecyloxirane-modified PAMAM G1
Type Polymer
Formula
Role core
2

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]

mPEG2000-DMG
Type Polymer
Formula
Role layer
3

firefly luciferase-encoding mRNA

Type Biomolecule
Formula
Role loaded material

Applications

Area Application Nanomaterial Variant Source
genetic engineering

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Biological effects

Biological system Test details Nanomaterial Variant Source
baby hamster kidney fibroblasts (BHK21 cells)

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  • 2-tridecyloxirane-modified poly(amido amine) dendrimer generation 1
  1. m1wE48yH1lhbDcMAhG
Product

mRNA-loaded modified dendrimer nanoparticles

Size: not specified

Medium/Support: none

References

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