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triple-hybridized yolk-shell organosilica nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

silicon dioxide

silicic oxide silica
Type Single Compound
Formula SiO2
Role core
2

bis-1,2-(triethoxysilyl)ethane moiety

1,2-bis(triethoxysilyl)-ethane moiety 1,2-bis(triethoxysilyl)ethane moiety 1,2-bis(trioxysilyl)ethane moiety bis(triethoxysilyl)ethane moiety 1,2-bis(triethoxysilyl) moiety 1,2-bis(oxysilyl)ethane group ethylene oxycarbosilane unit ethane-1,2-bis(siloxy) group 1,2-ethanebis(siloxy) group 1,2-bis(trioxysilyl)ethane BTSE-derived moiety BTMSE moiety BTESE moiety BTEE moiety BTEB moiety BESE moiety BTSE moiety BES moiety
Type Single Compound
Formula -C2H4O6Si2-
Role framework element
3

1,4-bis(triethoxysilyl)propane tetrasulfide moiety

1,4-bis(triethoxysilyl)propane tetrasulfide moiety 1,4-bis(triethoxysily)propane tetrasulfide moiety bis[3-(triethoxysilyl)propyl]tetrasulfide moiety bis[3-(trioxysilyl)propyl]tetrasulfide moiety bis(triethoxysilylpropyl)tetrasulfide moiety bis(trioxysilylpropyl)tetrasulfide moiety TESPTS-derived moiety BTES-4S moiety BTEPTS moiety TESPTS moiety TESPT moiety BTES moiety BTTS moiety
Type Single Compound
Formula -C6H12O6S4Si2-
Role framework element
4

1,4-bis(triethoxysilyl)benzene moiety

1,4-bis(trioxysilyl)-benzene moiety bis(triethoxysilyl)phenylene moiety 1,4-bis(trioxysilyl)benzene moiety 1,4-bis(silyl)benzene fragment bis(trioxysilyl)benzene moiety 1,4-benzenebis(siloxy) group BTSB-derived moiety BTESB moiety BTEB moiety BTEP moiety BTSB moiety BTB moiety
Type Single Compound
Formula -C6H4O6Si2-
Role framework element
5

water

Type Single Compound
Formula H2O
Role layer
6

silicon dioxide

silicic oxide silica
Type Single Compound
Formula SiO2
Role layer
7

bis-1,2-(triethoxysilyl)ethane moiety

1,2-bis(triethoxysilyl)-ethane moiety 1,2-bis(triethoxysilyl)ethane moiety 1,2-bis(trioxysilyl)ethane moiety bis(triethoxysilyl)ethane moiety 1,2-bis(triethoxysilyl) moiety 1,2-bis(oxysilyl)ethane group ethylene oxycarbosilane unit ethane-1,2-bis(siloxy) group 1,2-ethanebis(siloxy) group 1,2-bis(trioxysilyl)ethane BTSE-derived moiety BTMSE moiety BTESE moiety BTEE moiety BTEB moiety BESE moiety BTSE moiety BES moiety
Type Single Compound
Formula -C2H4O6Si2-
Role framework element
8

1,4-bis(triethoxysilyl)propane tetrasulfide moiety

1,4-bis(triethoxysilyl)propane tetrasulfide moiety 1,4-bis(triethoxysily)propane tetrasulfide moiety bis[3-(triethoxysilyl)propyl]tetrasulfide moiety bis[3-(trioxysilyl)propyl]tetrasulfide moiety bis(triethoxysilylpropyl)tetrasulfide moiety bis(trioxysilylpropyl)tetrasulfide moiety TESPTS-derived moiety BTES-4S moiety BTEPTS moiety TESPTS moiety TESPT moiety BTES moiety BTTS moiety
Type Single Compound
Formula -C6H12O6S4Si2-
Role framework element
9

1,4-bis(triethoxysilyl)benzene moiety

1,4-bis(trioxysilyl)-benzene moiety bis(triethoxysilyl)phenylene moiety 1,4-bis(trioxysilyl)benzene moiety 1,4-bis(silyl)benzene fragment bis(trioxysilyl)benzene moiety 1,4-benzenebis(siloxy) group BTSB-derived moiety BTESB moiety BTEB moiety BTEP moiety BTSB moiety BTB moiety
Type Single Compound
Formula -C6H4O6Si2-
Role framework element

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
ICR mouse

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • 1,4-bis(triethoxysilyl)benzene
  • bis-1,2-(triethoxysilyl)ethane
  • 1,4-bis(triethoxysilyl)propane tetrasulfide
See all (4)
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Product

triple-hybridized yolk-shell organosilica nanoparticles

Diameter: 160 nm

Size: 60 nm

Thickness: 21 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • 1,4-bis(triethoxysilyl)benzene
  • bis-1,2-(triethoxysilyl)ethane
  • 1,4-bis(triethoxysilyl)propane tetrasulfide
See all (4)
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Product

triple-hybridized yolk-shell organosilica nanoparticles

Diameter: 220 nm

Size: 80 nm

Thickness: 30 nm

Medium/Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • 1,4-bis(triethoxysilyl)benzene
  • bis-1,2-(triethoxysilyl)ethane
  • 1,4-bis(triethoxysilyl)propane tetrasulfide
See all (4)
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Product

triple-hybridized yolk-shell organosilica nanoparticles

Diameter: 310 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
Product

triple-hybridized yolk-shell organosilica nanoparticles

Diameter: 290 nm

Hydrodynamic diameter: ~ 350 nm

Pore size: 2.5 - 38 nm

Size: 110 nm

Thickness: 45 nm

Medium: Dulbecco's modified Eagle medium

Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • 1,4-bis(triethoxysilyl)benzene
  • bis-1,2-(triethoxysilyl)ethane
  • 1,4-bis(triethoxysilyl)propane tetrasulfide
See all (4)
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Product

triple-hybridized yolk-shell organosilica nanoparticles

Diameter: 360 nm

Medium/Support: none

References

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