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PTX/Cypate-loaded poly(ethylene glycol)-a-poly(ε-caprolactone)-SS-poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide) nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

poly(ethylene glycol)-a-poly(ε-caprolactone)-SS-poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide) nanoparticles

PEG-a-PCL-SS-P(NIPAM-co-DMA) NP
Type Nano Material
Formula
Role carriers
2

Paclitaxel

Plaxicel Abraxane Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material
3

cypate

cypate
Type Single Compound
Formula C41H40N2O4
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on DTT presence

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
4T1 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cypate
  • poly(ethylene glycol)-a-poly(ε-caprolactone)-SS-poly(N,N-dimethylacrylamide)
  • Paclitaxel
  1. oIps
  2. zLQYs
  3. 7ZtQ5R8jSe
  4. acyy
Product

PTX/Cypate-loaded poly(ethylene glycol)-a-poly(ε-caprolactone)-SS-poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide) nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • cypate
  • poly(ethylene glycol)-a-poly(ε-caprolactone)-SS-poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide)
  • Paclitaxel
  1. vaou
  2. Jjs2E
  3. GOC0PowApG
  4. G7KG
Product

PTX/Cypate-loaded poly(ethylene glycol)-a-poly(ε-caprolactone)-SS-poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide) nanoparticles

Diameter: ~ 100 nm

Medium/Support: none

References

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