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fluorescein isothiocyanate-loaded poly(lactic acid-co-glycolic acid) nanoparticles

Based on

2 Articles
1 Patents
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

PLGA 7520

Type Polymer
Formula
Role carriers
2

3',6'-dihydroxy-5-isothiocyanato-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one

fluorescein-5-isothiocyanate fluorescein isothiocyanate FITC
Type Single Compound
Formula C21H11NO5S
Role loaded material

Applications

Area Application Nanomaterial Variant Source
diagnostics

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Biological effects

Biological system Test details Nanomaterial Variant Source
Japanese rabbit with surgically induced unilateral hind limb ischemia

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)
  • 3',6'-dihydroxy-5-isothiocyanato-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one
  1. 4ERfqTb0a0OimKWX
  2. pc1HME96
Product

fluorescein isothiocyanate-loaded poly(lactic acid-co-glycolic acid) nanoparticles

Diameter: ~ 100 - 200 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • 3',6'-dihydroxy-5-isothiocyanato-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one
  • poly(DL-lactic-co-glycolic acid)
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  2. KBEVR
  3. YW8F8AscU
Product

fluorescein isothiocyanate-loaded poly(lactic acid-co-glycolic acid) nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • PLGA 7520
  • 3',6'-dihydroxy-5-isothiocyanato-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one
  1. ptOJ48fdL1addYpYFPYJVbwq2U
Product

fluorescein isothiocyanate-loaded poly(lactic acid-co-glycolic acid) nanoparticles

Size: not specified

Medium/Support: none

References

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