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Pt-prodrug-loaded poly(ε-caprolactone)-block-poly(2-aminoethylethylene phosphate) nanoparticles

Based on

2 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

carbon dots

CD
Type Nano Material
Formula
Role carriers
2

4-[(diaminodichlorohydroxyplatinio)oxy]-4-oxobutanoic acid

c,c,t-[Pt(NH3)2Cl2 (OOCCH2CH2COOH) (OH)] c,c,t-[Pt(NH3)2Cl2(OH)(O2CCH2CH2CO2H)] cisplatin prodrug Cis-Pt(NH3)2Cl2 SCP DSP
Type Single Compound
Formula C4H12Cl2N2O5Pt
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
A549 lung carcinoma cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • 4-[(diaminodichlorohydroxyplatinio)oxy]-4-oxobutanoic acid
  1. mod
  2. DZfc08FeDXaLM6Xdto6ynN2chRJlQJIhMINCdyTFL0xyFNQx41oKX48C583uO
  3. QMoZH
Product

Pt-prodrug-loaded poly(ε-caprolactone)-block-poly(2-aminoethylethylene phosphate) nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
  1. saW02QqJFIEgsCnG6lWxBylqMeaFIw65DgVnHTpOoIPOIVpxJRcW6Cg9JwkV
  2. MwFs04AWHYGXF1KZTBZM
  3. 67Nzv
Product

Pt-prodrug-loaded poly(ε-caprolactone)-block-poly(2-aminoethylethylene phosphate) nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Product

Pt-prodrug-loaded poly(ε-caprolactone)-block-poly(2-aminoethylethylene phosphate) nanoparticles

Hydrodynamic diameter: ~ 20 - ~ 40 nm

Medium: water

Support: none

References

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