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PEGlyated NPAPF@SiO2-FA NP

Based on

1 Articles
2016 Most recent source

Composition

1

bis(4-(N-(2-naphthyl)phenylamino)phenyl)-fumaronitrile

NPAPF
Type Single Compound
Formula C48H32N4
Role core
2

silicon dioxide

silicic oxide silica
Type Single Compound
Formula SiO2
Role layer
3

(3-aminopropyl)trimethoxysilane moiety

(3-aminopropyl)trimethoxysilane moiety (3-aminopropyl)triethoxysilane moiety γ-aminopropyltriethoxy silane moiety 3-aminopropyltrimethoxysilane moiety γ-aminopropyltriethoxysilane moiety 3-aminopropyltriethoxysilane moiety (3-aminopropyl)trioxysilane moiety (3-aminopropyl)silanetrioxy group 3-aminopropylsilanetrioxy group 3-aminopropylsiloxy fragment 3-aminopropyl silane moiety 3-aminopropylsilane moiety γ-APTES moiety 3-APTS moiety APTES moiety APTMS moiety AMPS moiety APTS moiety APS moiety
Type Single Compound
Formula -C3H8NO3Si-
Role layer
4

folate acid

folic acid folate FOL FA
Type Single Compound
Formula C19H19N7O6
Role layer
5

poly(maleicanhydride-alt-1-octadecene)-poly(-ethyleneglycol)

C18PMH-PEG
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c mouse xenografted with mammary carcinoma 4T1 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

PEGlyated NPAPF@SiO2-FA NP

Size: ~ 120 nm

Medium: aqueous solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
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  2. jCC6pKBuriutCkI
Product

PEGlyated NPAPF@SiO2-FA NP

Hydrodynamic diameter: ~ 120 nm

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
Product

PEGlyated NPAPF@SiO2-FA NP

Size: ~ 130 nm

Medium: aqueous solution

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
Product

PEGlyated NPAPF@SiO2-FA NP

Size: ~ 130 nm

Medium: serum

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
Product

PEGlyated NPAPF@SiO2-FA NP

Size: ~ 130 nm

Medium: aqueous solution

Support: none

References

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