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docetaxel-loaded poly(acrylic acid)-decorated poly(glycidyl methacrylate) nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

PGMA

Type Polymer
Formula
Role core
2

poly(acrylic acid)

PAA
Type Polymer
Formula
Role layer
3

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on with or without Tween additive

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
T11 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

docetaxel-loaded poly(acrylic acid)-decorated poly(glycidyl methacrylate) nanoparticles

Hydrodynamic diameter: 138.1 - 167.9 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  • PGMA
  1. kPrCR2W71H0FhWhHCEPMJ
  2. lUjnOVYA8Juu7F4Fwra
  3. Vt1FhWdEC0Iv9i
  4. oefgmJgbL3L92wQ
Product

docetaxel-loaded poly(acrylic acid)-decorated poly(glycidyl methacrylate) nanoparticles

Size: not specified

Medium/Support: none

References

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