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TNFα siRNA-encapsulated nanoemulsion formulation

Based on

1 Articles
2016 Most recent source

Composition

1

water

Type Single Compound
Formula H2O
Role raw materials
2

siRNA-encapsulated flaxseed oil-containing cationic micelles

Type Nano Material
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability to RNAse treatment

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
adherent murine macrophage J774A.1 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecenoyloxy]-1-propanaminium
  1. XjusVPHHhTbotqfg
Product

TNFα siRNA-encapsulated nanoemulsion formulation

Size: 361.3 - 469.3 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecenoyloxy]-1-propanaminium
  1. oeYjH9UqHzf5k41q
Product

TNFα siRNA-encapsulated nanoemulsion formulation

Size: 350 nm

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecenoyloxy]-1-propanaminium
  1. sFAtyMzJj5wHbJyp
Product

TNFα siRNA-encapsulated nanoemulsion formulation

Size: 360.7 - 412.7 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecenoyloxy]-1-propanaminium
  1. b1CXvxWK6wmG96AZ
Product

TNFα siRNA-encapsulated nanoemulsion formulation

Size: not specified

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecenoyloxy]-1-propanaminium
  1. sCCSqBSe0ra29SXG
Product

TNFα siRNA-encapsulated nanoemulsion formulation

Droplet size: 69 - 168 nm

Size: 362.2 - 418.2 nm

Medium/Support: none

References

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