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Ce6-loaded RGD and TAT peptides-modified mesoporous silica nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

mesoporous silica nanoparticles

amine-functionalized MSN positively charged MSN NH2-functionalized MSN MSN
Type Nano Material
Formula
Role core
2

fluorescein isothiocyanate-labeled TAT peptide

(FITC)-C6-TAT
Type Biomolecule
Formula
Role layer
3

polyoxyethylene-maleimide

PEG1500-MAL
Type Polymer
Formula
Role layer
4

cyclic(arginine-glycine-aspartic acid-D-tyrosine-cysteine) peptide

cyclic(arginine-glycine-aspartic acid-D-tyrosine-cysteine) cyclo(Arg-Gly-Asp-DTyr-Cys) peptide cyclo-(Arg-Gly-Asp-D-Tyr-Cys) cyclo(Arg-Gly-Asp-D-Tyr-Cys) c(RGDyC) peptide c(RGDyC)
Type Single Compound
Formula C24H34N8O8S
Role layer
5

(17S,18S)-18-(2-carboxyethyl)-20-(carboxymethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18,22,23-tetrahydroporphyrin-2-carboxylic acid

13-carboxy-17-(2-carboxyethyl)-15-carboxymethyl-17,18-trans-dihydro-3-vinyl-8-ethyl-2,7,12,18-tetramethylporphyrin chlorin e6 Chlorin e6 Chlorin Ce6
Type Single Compound
Formula C34H36N4O6
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Ce6 release dependent on pH

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Catalytic properties

Reaction Value Nanomaterial Variant Source
singlet oxygen generation under light irradiation

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
UV

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c nude mouse with HeLa cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
  1. 7e1NsmG1fbsjD0zSWuly4C
  2. I3J6JRRXAe
Product

Ce6-loaded RGD and TAT peptides-modified mesoporous silica nanoparticles

Size: not specified

Medium/Support: none

References

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