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poly(DMAEMA)-b-poly(DMAEMA-PAA-BMA) nanoparticle-small interfering RNA complexes

Based on

2 Articles
2018 Most recent source

Composition

1

poly(2-dimethylaminoethyl methacrylate)-block-poly(2-dimethylaminoethyl methacrylate-propylacrylic acid-butyl methacrylate)

poly(DMAEMA)-b-poly(DMAEMA-PAA-BMA)
Type Polymer
Formula
Role raw materials
2

small interfering ribonucleic acid

small interfering RNA siRNA
Type Biomolecule
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
ability of siRNA displacement with heparin

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
bovine serum albumin (BSA)

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Preparation

Method 1

Type: Physical formation
Source:
Product

poly(DMAEMA)-b-poly(DMAEMA-PAA-BMA) nanoparticle-small interfering RNA complexes

Diameter: 3.9 - 10.7 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Product

poly(DMAEMA)-b-poly(DMAEMA-PAA-BMA) nanoparticle-small interfering RNA complexes

Size: not specified

Medium: Dulbecco's modified Eagle medium with fetal bovine serum

Support: none

Method 3

Type: Physical formation
Source:
Product

poly(DMAEMA)-b-poly(DMAEMA-PAA-BMA) nanoparticle-small interfering RNA complexes

Size: not specified

Medium: Dulbecco's modified Eagle medium with fetal bovine serum

Support: none

Method 4

Type: Physical formation
Source:
Product

poly(DMAEMA)-b-poly(DMAEMA-PAA-BMA) nanoparticle-small interfering RNA complexes

Hydrodynamic diameter: ~ 70 nm

Medium: OptiMEM I medium

Support: none

Method 5

Type: Physical formation
Source:
Product

poly(DMAEMA)-b-poly(DMAEMA-PAA-BMA) nanoparticle-small interfering RNA complexes

Size: not specified

Medium: OptiMEM I medium

Support: none

References

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