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hyperbranched 2,2-bis-(hydroxymethyl)propionic acid polyester/miRNA polyplexes

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

PEG-hyperbranched polyester-PEI co-polymer

Type Polymer
Formula
Role core
2

microRNA

miR-26a
Type Biomolecule
Formula
Role layer
3

PEG-hyperbranched polyester-PEI co-polymer

Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
primary mouse osteoblasts

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • PEG-hyperbranched polyester-PEI co-polymer
  • microRNA
  1. fC3WM3FiXEEj1ZHa
Product

hyperbranched 2,2-bis-(hydroxymethyl)propionic acid polyester/miRNA polyplexes

Diameter: 36 nm

Thickness: 13 nm

Thickness: 14 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
  1. ftubOJHTxi
Product

hyperbranched 2,2-bis-(hydroxymethyl)propionic acid polyester/miRNA polyplexes

Size: ~ 140 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • PEG-hyperbranched polyester-PEI co-polymer
  • microRNA
  1. Ld1u1tnDNFArzgWQ
Product

hyperbranched 2,2-bis-(hydroxymethyl)propionic acid polyester/miRNA polyplexes

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
  1. 0wFudOU1Mo
Product

hyperbranched 2,2-bis-(hydroxymethyl)propionic acid polyester/miRNA polyplexes

Size: ~ 110 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • PEG-hyperbranched polyester-PEI co-polymer
  • microRNA
  1. DUKsP8RLAToJ1mG2
Product

hyperbranched 2,2-bis-(hydroxymethyl)propionic acid polyester/miRNA polyplexes

Size: not specified

Medium/Support: none

References

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