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siRNA against luciferase-loaded zwitterionic amino lipid nanoparticles

Based on

26 Articles
2018 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

zwitterionic amino lipid nanoparticles

ZAL nanoparticles ZAL NP ZNP
Type Nano Material
Formula
Role carriers
2

siRNA against luciferase

siLuc
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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transmission electron microscopy

Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c mouse bearing MDA-MB-231 xenograft

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • small interfering RNA
  • ethylenediamine/alkylamine-conjugated polyglutamate amine
  1. vv3yn
Product

siRNA against luciferase-loaded zwitterionic amino lipid nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • Cy5-labeled small interfering RNA
  • ethylenediamine/alkylamine-conjugated polyglutamate amine
  1. IeOW0
Product

siRNA against luciferase-loaded zwitterionic amino lipid nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • γ-aminohexane-diaminoethane-L-polyglutamate
  • Plk1 siRNA
  1. j9LYk
Product

siRNA against luciferase-loaded zwitterionic amino lipid nanoparticles

Diameter: 25 - 90 nm

Hydrodynamic diameter: 31 - 55 nm

Medium/Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • {5'-CUUACGCUGAGUACUUCGAdTdT-3'}*{5'-UCGAAGUACUCAGCGUAAGdTdT-3'}
  1. qFRcSALVbS4v2QyidAMQlQgmPBPHFT
  2. sHunZH3poB
  3. ZKe32QYdA
  4. thWdE
  5. cmyg2VE24R
Product

siRNA against luciferase-loaded zwitterionic amino lipid nanoparticles

Size: not specified

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • micro RNA
  • ethylenediamine/alkylamine-conjugated polyglutamate amine
  1. F11qd
Product

siRNA against luciferase-loaded zwitterionic amino lipid nanoparticles

Size: not specified

Medium/Support: none

References

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