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fluorescein isothiocyanate-labeled TRAIL/cilengitide-loaded core-shell nanogel particles

Based on

1 Articles
2016 Most recent source

Composition

1

fluorescein isothiocyanate-labeled TRAIL/cilengitide-loaded nanogel particles

FITC-labeled TRAIL/cilengitide-loaded NG particles
Type Nano Material
Formula
Role core
2

transglutaminase-encapsulated nanogel particles

TG-encapsulated NG particles
Type Nano Material
Formula
Role layer
3

4-[(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]cyclohexane-1-carbonyl group

(succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate) moiety N-succinimidyl 4-(maleimidomethyl)cyclohexanecarboxylate unit succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate 4-(N-maleimidomethyl)cyclohexane-1-carboxylic acid moiety 4-(N-maleimidomethyl)cyclohexane-1-carboxylate moiety 4-(N-maleimidomethyl)cyclohexane-1-carbonyl moiety 4-(N-maleimidomethyl)cyclohexane-1-carbonyl group 4-(N-maleimidomethyl)cyclohexane-1-carbonyl sulfo-SMCC linker sulfo-SMCC moiety Sulfo-SMCC moiety sulfo-SMCC unit SMCC moiety SMCC spacer SMCC unit
Type Single Compound
Formula -C12H14NO3
Role layer
4

HSA

Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
enzyme-induced peptide release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human breast adenocarcinoma MDA-MB-231 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • N-(3-aminopropyl)-methacrylamide
  • c(RGDf(NMe)V)
  • fluorescein isothiocyanate-labeled tumor necrosis factor-related apoptosis-inducing ligand
See all (5)
  1. dH6oMffRKYvZKS9UJFeHKieQM2m5Pkof9gUyIgkQC
  2. I7uvlOMxnegoyd3OZ5aG1qdRyYtD47yP3KaHtm
  3. BRtKyXARk5FS4H0xuW0JFe7v0LKvh4cHi38V7HuEGARSuOxB1fbQ0r5uFRI1IeUZaGWEG
  4. 9Q5b0nawY6MeRIq5O9prYHfzWx2xxU9LmtDeXlrTZyM4U0TWczEBpcAhQI
  5. iRa7HbCkma4mpNnnpqsRzsQ9DJ
  6. E6p9
Product

fluorescein isothiocyanate-labeled TRAIL/cilengitide-loaded core-shell nanogel particles

Size: ~ 123 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Product

fluorescein isothiocyanate-labeled TRAIL/cilengitide-loaded core-shell nanogel particles

Hydrodynamic diameter: ~ 80 - ~ 170 nm

Size: ~ 123 nm

Medium/Support: none

References

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