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PAsp-based vector/pDNA complexes

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

star-shaped poly(aspartic acid)-poly(2-(dimethylamino)ethyl methacrylate)-NH2

s-PAsp-PDM-NH2
Type Polymer
Formula
Role raw materials
2

pRL-CMV plasmid DNA

pRL-CMV
Type Biomolecule
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
COS-7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • pRL-CMV plasmid DNA
  • linear poly(aspartic acid)-poly(2-(dimethylamino)ethyl methacrylate)-NH2
  1. cRm0G9zSr2JhabqoF8jhTcnCzVE5SaQmLm
Product

PAsp-based vector/pDNA complexes

Hydrodynamic diameter: ~ 200 - 500 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • pRL-CMV plasmid DNA
  • linear poly(aspartic acid)-poly(2-(dimethylamino)ethyl methacrylate)-NH2
  1. cibsdfTNb3qBQuXsdOp9R1o9hx7kfvf92c
Product

PAsp-based vector/pDNA complexes

Hydrodynamic diameter: ~ 200 nm

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • pRL-CMV plasmid DNA
  • star-shaped poly(aspartic acid)-poly(2-(dimethylamino)ethyl methacrylate)-OH
  1. 5WD202qyGBaTXtNVthZy6TIGVWMS66vMcg
Product

PAsp-based vector/pDNA complexes

Hydrodynamic diameter: ~ 180 - 220 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • star-shaped poly(aspartic acid)-poly(2-(dimethylamino)ethyl methacrylate)-OH
  • pEGFP-N1 plasmid DNA
  1. pQaxDd5lbihXxpfARWnzWQI2COvYsTxmXV
Product

PAsp-based vector/pDNA complexes

Size: not specified

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • linear poly(aspartic acid)-poly(2-(dimethylamino)ethyl methacrylate)-OH
  • pRL-CMV plasmid DNA
  1. rei4p5GBliGt7e2orW9Ady6U0ANkbKRIYL
Product

PAsp-based vector/pDNA complexes

Hydrodynamic diameter: ~ 200 nm

Medium/Support: none

References

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