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DOX loaded DLC-PEG nanoassemblies

Based on

1 Articles
2014 Most recent source

Composition

1

polyaminoester dendrimer

Type Nano Material
Formula
Role core
2

cholesterol

Type Single Compound
Formula C27H46O
Role layer
3

(2-aminoethoxy)({2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy})phosphinic acid

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine 1,2-dioleoyl-sn-glycero-3-phosphatidyl-ethanolamine 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine 1,2-dioleyl-sn-glycerophosphoethanolamine dioleoyl-phosphatidyl ethanolamine dioleoyl-phosphatidylethanol-amine dioleoylphosphatidylethanolamine DOPA DOPE
Type Single Compound
Formula C41H78NO8P
Role layer
4

DSPE-PEG

Type Polymer
Formula
Role layer
5

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Biological effects

Biological system Test details Nanomaterial Variant Source
BCAP-37 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • cholesterol
  • (2-aminoethoxy)({2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy})phosphinic acid
  • DSPE-PEG
  1. BLcNAETzZpUtSPNEEdYf9
Product

DOX loaded DLC-PEG nanoassemblies

Diameter: 40 - 50 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

DOX loaded DLC-PEG nanoassemblies

Diameter: 40 - 50 nm

Medium: trehalose solution

Support: none

References

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