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PTX nanocrystallites

Based on

1 Articles
2015 Most recent source

Composition

1

Paclitaxel

Plaxicel Abraxane Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role core
2

poly(ethylene glycol)-b-poly (propylene glycol)-b-poly (ethylene glycol)

PEG-b-PPG-b-PEG Pluronic F127
Type Polymer
Formula
Role layer
3

cyanine 5-NHS

Cy5.0-NHS cyanine 5 cyanine5 Cy5-NHS Cy5
Type Single Compound
Formula C36H41N3O10S2
Role dopant

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
dispersion stability in water

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Biological effects

Biological system Test details Nanomaterial Variant Source
3D multicellular tumor spheroid of breast cancer 4T1 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • Paclitaxel
  • cyanine 5-NHS
  1. yNKjqJQxWucfTvT0SBVd2w1miC
Product

PTX nanocrystallites

Size: 6.2 - 11.0 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • Paclitaxel
  • cyanine 5-NHS
  1. BIwFj1ByhCqTFU8sprDohZyL29
Product

PTX nanocrystallites

Size: 52.5 - 86.3 nm

Medium/Support: none

References

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