Loading ...

GW3965-loaded poly(D,L-lactide)-b-poly(ethylene glycol) nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

3-[3-[N-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride

liver X receptor agonist GW3965 LXR agonist GW3965 GW3965
Type Single Compound
Formula C33H32Cl2F3NO3
Role core
2

poly(D,L-lactide)-b-poly(ethylene glycol)

PLA9K-PEG2K PLA-PEG
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
encapsulation efficiency

More information/entries available to subscribers only.

Or, view sample content

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

More information available to subscribers only.

Or, view sample content

Biological effects

Biological system Test details Nanomaterial Variant Source
mouse peritoneal macrophages

More information available to subscribers only.

Or, view sample content

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(D,L-lactide)-b-poly(ethylene glycol)
  • 3-[3-[N-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride
  1. QwgnFlVbIIb4vwUWoGg67Gz
Product

GW3965-loaded poly(D,L-lactide)-b-poly(ethylene glycol) nanoparticles

Hydrodynamic diameter: 109.9 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Product

GW3965-loaded poly(D,L-lactide)-b-poly(ethylene glycol) nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • poly(D,L-lactide)-b-poly(ethylene glycol)
  • 3-[3-[N-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride
  1. MGMnpNev5zV80HknWvv1Mwa
Product

GW3965-loaded poly(D,L-lactide)-b-poly(ethylene glycol) nanoparticles

Hydrodynamic diameter: 108.9 nm

Medium: water

Support: none

References

Full content is available to subscribers only

To view content please choose from the following:


Sign up for a free trial