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2'-OMe-phosphorodithioate-modified siGRAMD1B-loaded DOPC liposomal nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine

Δ9-cis-1,2-dioleoyl-sn-glycero-3-phosphocholine 1,2-dioleoyl- sn-glycero-3-phosphatidylcholine 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine 1,2-dioctanoyl-sn-glycero-3-phosphocholine 1,2- dioleoyl-sn-glycero-3-phosphocholine 1,2-dioleoyl-sn-glycero-3- phosphocholine 1,2-dioleoyl-sn-glycero-3-phosphocholine Δ9-cis-sn-glycero-3-phosphocholine dioleoyl-phosphatidyl choline dioleoylglycerophosphocholine dioleoylphosphatidylcholine dioleoylphosphocholine 18:1 (Δ9-cis) PC 18:1(cis) PC DC18:1PC DOPC PC
Type Single Compound
Formula C44H84NO8P
Role layer
3

2'-OMe-phosphorodithioate-modified siGRAMD1B

MePS2-1 siGRAMD1B
Type Complex Compound
Formula
Role loaded material

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Biological effects

Biological system Test details Nanomaterial Variant Source
mouse bearing human ovarian cancer (HeyA8-MDR)

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • 2'-OMe-phosphorodithioate-modified siGRAMD1B
  • 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
  1. xLUj0jOTXPhvzMSX
Product

2'-OMe-phosphorodithioate-modified siGRAMD1B-loaded DOPC liposomal nanoparticles

Size: not specified

Medium/Support: none

References

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