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coumarin 6-loaded PGA-based nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

3-(1,3-benzothiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one

3-(2-benzothiazolyl)-N,N-diethylumbelliferylamine 3-(2-benzothiazolyl)-7-(diethylamino)coumarin 6-coumarin coumarin 6 coumarin-6 C6 dye Cou6 C-6
Type Single Compound
Formula (CH3CH2)2NC8H4OCOC7H4NS
Role loaded material
3

poly(methyl ethylene glycol-g-glutamate)-co-poly(distearin-g-glutamate) copolymer

mPEGGM-PDSGM
Type Polymer
Formula
Role layer

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
mouse brain microvascular endothelial (bEnd3) cell and rat astrocytes (CTX TNA2) cell co-culture (BBB model)

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(methyl ethylene glycol-g-glutamate)-co-poly(distearin-g-glutamate) copolymer
  • 3-(1,3-benzothiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one
  • phosphate buffer solution
  1. OJWpPItzkC3nVhlLiLvkn5b0SY
Product

coumarin 6-loaded PGA-based nanoparticles

Geometric radius: 90.6 - 91.6 nm

Gyration radius: 88.7 - 90.3 nm

Hydrodynamic diameter: 141.4 - 143.0 nm

Medium/Support: none

References

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