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doxorubicin loaded DNA duplex complex with modified protamine

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

ATP aptamer/cDNA duplex

Type Biomolecule
Formula
Role raw materials
2

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role raw materials
3

acrylamide-modified protamine

m-protamine
Type Biomolecule
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
MDA-MB-231 tumor-bearing female nude J:NU mouse

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • ATP aptamer/cDNA duplex
  • adriblastin
  1. FBE9bKVa0hrnB7Ys
Product

doxorubicin loaded DNA duplex complex with modified protamine

Hydrodynamic diameter: ~ 150 nm

Medium/Support: none

References

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