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Pc4-loaded σ-2 receptor targeting-ligand functionalized triple-responsive expansile nanogel particles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

MBA-PDA-PEG-PNiPMA

Type Polymer
Formula
Role carriers
2

silicon phthalocyanine photosensitizer Pc 4

Pc 4 Pc4
Type Single Compound
Formula C40H37N9OSi2
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
transition temperature

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Biological effects

Biological system Test details Nanomaterial Variant Source
head and neck squamous cell carcinoma UMSCC22A cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly[(2-(pyridin-2-yldisulfanyl))-co-[poly(ethylene glycol)]]-poly(N-isopropyl methacrylamide)
  • silicon phthalocyanine photosensitizer Pc 4
  • 4-methoxybenzoic acid-poly[(2-(pyridin-2-yldisulfanyl))-co-[poly(ethylene glycol)]]-poly(N-Isopropyl methacrylamide)
  1. pK2qQwUHbpECSRb
  2. ZTHbrXJnQnEOfXzqWNgFJ0aygfOjxsqHa57DTwU5bi7O
  3. BXlFfs
Product

Pc4-loaded σ-2 receptor targeting-ligand functionalized triple-responsive expansile nanogel particles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • poly[(2-(pyridin-2-yldisulfanyl))-co-[poly(ethylene glycol)]]-poly(N-isopropyl methacrylamide)
  • silicon phthalocyanine photosensitizer Pc 4
  • 4-methoxybenzoic acid-poly[(2-(pyridin-2-yldisulfanyl))-co-[poly(ethylene glycol)]]-poly(N-Isopropyl methacrylamide)
  1. ibrtZOjKH6W9Hxk
  2. H0AnTQh0mNYkpIXZq0Ao1EkdvRG5AXT98GKAb6EJCLbG
  3. tOhLVh
Product

Pc4-loaded σ-2 receptor targeting-ligand functionalized triple-responsive expansile nanogel particles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • poly[(2-(pyridin-2-yldisulfanyl))-co-[poly(ethylene glycol)]]-poly(N-isopropyl methacrylamide)
  • silicon phthalocyanine photosensitizer Pc 4
  • 4-methoxybenzoic acid-poly[(2-(pyridin-2-yldisulfanyl))-co-[poly(ethylene glycol)]]-poly(N-Isopropyl methacrylamide)
  1. GcjgWk6cSQ9bEcd
  2. E2XEwbHMgnHtUxNwum8h404HVxp6mdoh8A7J2qe2B6OB
  3. YWy8rj
Product

Pc4-loaded σ-2 receptor targeting-ligand functionalized triple-responsive expansile nanogel particles

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • poly[(2-(pyridin-2-yldisulfanyl))-co-[poly(ethylene glycol)]]-poly(N-isopropyl methacrylamide)
  • silicon phthalocyanine photosensitizer Pc 4
  • 4-methoxybenzoic acid-poly[(2-(pyridin-2-yldisulfanyl))-co-[poly(ethylene glycol)]]-poly(N-Isopropyl methacrylamide)
  1. qvHCt1ztrDTxhmu
  2. 6fFDBADHtLzBDRACF4U1hcdqkOEW0APuv8CW8z7ySAjg
  3. erJHip
Product

Pc4-loaded σ-2 receptor targeting-ligand functionalized triple-responsive expansile nanogel particles

Size: not specified

Medium/Support: none

References

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