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poly(tetraguanidinium-derived disulfide)-coated siRNA nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

siRNA

Type Biomolecule
Formula
Role raw materials
2

poly(tetraguanidinium-derived disulfide)

PTEGGu4
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Characterization

Method Nanomaterial Variant Source
circular dichroism

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
Product

poly(tetraguanidinium-derived disulfide)-coated siRNA nanoparticles

Size: 2.91 nm

Medium: none

Support: HEPES buffer

Method 2

Type: Chemical synthesis
Source:
Starting materials
Product

poly(tetraguanidinium-derived disulfide)-coated siRNA nanoparticles

Hydrodynamic diameter: 3.61 nm

Medium: none

Support: HEPES buffer

Method 3

Type: Chemical synthesis
Source:
Starting materials
Product

poly(tetraguanidinium-derived disulfide)-coated siRNA nanoparticles

Hydrodynamic diameter: 7.91 nm

Medium: none

Support: HEPES buffer

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • tetraguanidinium-derived dithiol
  • phosphate buffer solution
  • siRNA
Product

poly(tetraguanidinium-derived disulfide)-coated siRNA nanoparticles

Hydrodynamic diameter: 3.02 nm

Medium: none

Support: phosphate buffer solution

References

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