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ctEGF targeted Au NP/RNase A/anti-MDR1 DNA nanocomplex

Based on

1 Articles
2014 Most recent source

Composition

1

gold

Type Single Compound
Formula Au
Role core
2

single-stranded deoxyribonucleic acid

anti-MDR1 DNA ssDNA
Type Biomolecule
Formula
Role layer
3

amino-modified single-stranded deoxyribonucleic acid

amino-modified anti-MDR1 DNA amino-modified ssDNA
Type Biomolecule
Formula
Role layer
4

NHS-PEG-maleimide crosslinker

Type Polymer
Formula
Role layer
5

[C4]-monothiol Cys-tagged EGF

epidermal growth factor ctEGF
Type Biomolecule
Formula
Role layer
6

ribonuclease A

RNase A
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability under proteinase K activity

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
firefly luciferase (Fluc) mRNA

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. WFhDr3jz5buamwCVwUhSA07dyPJdDv74EKgyt8VZyWMiil
  2. mcJZPWf
Product

ctEGF targeted Au NP/RNase A/anti-MDR1 DNA nanocomplex

Hydrodynamic diameter: 49.3 - 54.7 nm

Size: ~ 15 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  1. eihi3p4cmVmxaIDyW0TQwgX2NfcvGVEa4m8IYPLpWrlQPJ
  2. eDquRbj
Product

ctEGF targeted Au NP/RNase A/anti-MDR1 DNA nanocomplex

Size: ~ 15 nm

Medium: phosphate buffer solution

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  1. iEniqXtN3j85NGmImBz1uZtkeSUAldP1w9J1WNgeaF6CSc
  2. UieAxEx
Product

ctEGF targeted Au NP/RNase A/anti-MDR1 DNA nanocomplex

Hydrodynamic diameter: 48.1 - 53.9 nm

Size: ~ 15 nm

Medium: phosphate buffer solution

Support: none

Method 4

Type: Physical formation
Source:
Product

ctEGF targeted Au NP/RNase A/anti-MDR1 DNA nanocomplex

Size: ~ 15 nm

Medium/Support: none

References

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