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FolA-conjugated siRNA polyplexes

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

Cy5-labeled siAHA1

Cy5-labeled siRNA
Type Biomolecule
Formula
Role core
2

C-Stp4-K(Stp4-C)-dPEG24-FolA

Type Complex Compound
Formula
Role layer

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
human alveolar adenocarcinoma A549 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

FolA-conjugated siRNA polyplexes

Hydrodynamic diameter: 6.3 - 6.9 nm

Medium: HEPES buffer

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • C-Stp4-K(Stp4-C)-dPEG24-FolA
  • Cy7-labeled siAHA1
  1. GghfQZesAIvNalfttCH3GZFSV7asNA3JJJGoLe2AbRvrHNkLKX
  2. wUt
Product

FolA-conjugated siRNA polyplexes

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • Cy5-labeled siAHA1
  • C-Stp4-K(Stp4-C)-dPEG24-FolA
  1. TX4EfZrb4H6AzZgNBOfS5oNECIp2j0H6UI5QZvIGdDT9apkliD
  2. xPI
Product

FolA-conjugated siRNA polyplexes

Diameter: 4.7 - 5.9 nm

Medium/Support: none

References

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