Loading ...

siRNA-PTX loaded PEG-pp-PEI-PE micelles

Based on

1 Articles
2014 Most recent source

Composition

1

(2-aminoethoxy)({2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy})phosphinic acid

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine 1,2-dioleoyl-sn-glycero-3-phosphatidyl-ethanolamine 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine 1,2-dioleyl-sn-glycerophosphoethanolamine dioleoyl-phosphatidyl ethanolamine dioleoyl-phosphatidylethanol-amine dioleoylphosphatidylethanolamine DOPA DOPE
Type Single Compound
Formula C41H78NO8P
Role core
2

poly(iminoethylene)

polyethyleneimine polyaziridine PEI
Type Polymer
Formula
Role layer
3

MMP-2-cleavable peptide

Type Biomolecule
Formula
Role layer
4

poly(ethylene glycol)

poly(ethylene oxide) polyethylene glycol polyethylene oxide polyoxyethylene PEG PEO POE
Type Polymer
Formula
Role layer
5

siRNA

Type Biomolecule
Formula
Role layer
6

Paclitaxel

Plaxicel Abraxane Paxene Taxol PCL PAC PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability in serum

More information/entries available to subscribers only.

Or, view sample content

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

More information available to subscribers only.

Or, view sample content

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

More information/entries available to subscribers only.

Or, view sample content

Biological effects

Biological system Test details Nanomaterial Variant Source
A549 cells

More information available to subscribers only.

Or, view sample content

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • Hanks' balanced salt solution
  • PEG-pp-PEI-PE
  • Paclitaxel
Product

siRNA-PTX loaded PEG-pp-PEI-PE micelles

Hydrodynamic diameter: ~ 40 nm

Medium: Hanks' balanced salt solution

Support: none

References

Full content is available to subscribers only

To view content please choose from the following:

We use cookies to improve your experience with our site. More information

Sign up for a free trial