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irinotecan hydrochloride-loaded mesoporous silica nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

silicon dioxide

silicic oxide silica
Type Single Compound
Formula SiO2
Role raw materials
2

irinotecan hydrochloride

camptosar CPT-11
Type Single Compound
Formula C33H39ClN4O6
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c nude mouse bearing MCF-7/BCRP drug resistant xenograft tumor

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • water
  1. 8Pol39kPTO1tOH6Z
  2. LD5a
  3. TOIJ76W
Product

irinotecan hydrochloride-loaded mesoporous silica nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Product

irinotecan hydrochloride-loaded mesoporous silica nanoparticles

Hydrodynamic diameter: 79.8 - 98.0 nm

Medium: water

Support: none

References

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