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Dtx-loaded-Fe3O4 nanoparticles-modified-poly(glycidal methacrylate) multifunctional nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role raw materials
2

Fe3O4 nanoporous particles

iron oxide nanoparticles magnetite nanoparticles Fe3O4 nanoparticles Fe3O4 NP
Type Nano Material
Formula
Role partial layer
3

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
transverse magnetic resonance relaxivity

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
PC3 tumor bearing nude mice

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Preparation

Method 1

Type: Physical formation
Source:
Product

Dtx-loaded-Fe3O4 nanoparticles-modified-poly(glycidal methacrylate) multifunctional nanoparticles

Hydrodynamic diameter: 156 nm

Medium: Pluronic F108 solution

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • glycidyl (meth)acrylate
  1. xTZyJmWUkspysfMNte
  2. 1BkPKOX3NnnLnVGqsXFCUj9s27uhe62d4g6
Product

Dtx-loaded-Fe3O4 nanoparticles-modified-poly(glycidal methacrylate) multifunctional nanoparticles

Diameter: ~ 150 nm

Medium/Support: none

References

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