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doxorubicin-loaded poly(ethylene glycol)-b-poly(ε-caprolactone-g-poly(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acrylate-co-2-(dimethylamino)ethyl methacrylate) micelles

Based on

15 Articles
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(ethylene glycol)-b-poly(ε-caprolactone-g-poly(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acrylate) micelles

mPEG-b-(PCL-g-PDA30) micelles mPEG-b-(PCL-g-PDA) micelles
Type Nano Material
Formula
Role carriers
2

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
4T1 cells

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Preparation

Method 1

Type: Physical formation
Source:
  1. OtvXqlNzavvRaNB0p8B3HHWQh
  2. 9qMLNnUs
  3. rmK7
Product

doxorubicin-loaded poly(ethylene glycol)-b-poly(ε-caprolactone-g-poly(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acrylate-co-2-(dimethylamino)ethyl methacrylate) micelles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
  1. 5ZQ
  2. UlNljqHEEr
  3. Vrm
Product

doxorubicin-loaded poly(ethylene glycol)-b-poly(ε-caprolactone-g-poly(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acrylate-co-2-(dimethylamino)ethyl methacrylate) micelles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
  1. B3OdY
  2. 6GMumz6r
  3. hJaw
Product

doxorubicin-loaded poly(ethylene glycol)-b-poly(ε-caprolactone-g-poly(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acrylate-co-2-(dimethylamino)ethyl methacrylate) micelles

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • poly(ethylene glycol)-b-poly(ε-caprolactone-g-poly(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acrylate)
  • adriblastin
  1. qDiBkblNfz3tsKMuAXUGjTQShTvZ
Product

doxorubicin-loaded poly(ethylene glycol)-b-poly(ε-caprolactone-g-poly(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acrylate-co-2-(dimethylamino)ethyl methacrylate) micelles

Hydrodynamic diameter: 113 - 145 nm

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • adriblastin
  • poly(ethylene glycol)-b-poly(ε-caprolactone-g-poly(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acrylate-co-2-(dimethylamino)ethyl methacrylate)
  1. B5UX8CcVQfg6tLa4hh8P98ITJ2aW
Product

doxorubicin-loaded poly(ethylene glycol)-b-poly(ε-caprolactone-g-poly(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acrylate-co-2-(dimethylamino)ethyl methacrylate) micelles

Hydrodynamic diameter: 131 - 143 nm

Medium/Support: none

References

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