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Au-PEG-198.3/siRNA nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

gold

Type Single Compound
Formula Au
Role core
2

thiolated Bcl-2 small interfering RNA

thiolated Bcl-2 siRNA
Type Biomolecule
Formula
Role layer
3

poly(ethylene glycol) 2-mercaptoethyl ether acetic acid

COOH-PEG5000-SH
Type Polymer
Formula
Role layer
4

monoclonal antibodies against FAT1 antigen

mAb198.3
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
glutathione-mediated siRNA release

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/C mouse with cancer Colo-205 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. W2jJkDFe5ryM8SIMVWGkL0pM6qzUhms
  2. fB4Mc5DRWGNH9y99UBykSIoIEYyBZQOSG5JToRpcEuT8NrosjYjxZjsvh8XTlZ8RcYlVTQ4xGIJV96BtHpizEuuoajSdZ
Product

Au-PEG-198.3/siRNA nanoparticles

Size: ~ 2 - 5 nm

Medium/Support: none

References

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