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arginine/phenylalanine/histidine-modified generation 5 polyamidoamine dendrimer/EGFP plasmid DNA complex nanoparticles

Based on

3 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

arginine/phenylalanine-modified generation 5 polyamidoamine dendrimer

arginine/phenylalanine-G5 PAMAM dendrimer conjugate arginine/phenylalanine-modified G5 PAMAM dendrimer G5-Arg51Phe53
Type Nano Material
Formula
Role carriers
2

EGFP plasmid DNA

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability to DNase treatment

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Applications

Area Application Nanomaterial Variant Source
genetic engineering

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
COS7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. 8OMQWXVINJtCrk57QEcqLlQ7p4UxHO6a8603ZZhyRhwmIIcoiFN7o8bfbZF3VSYDQsv1ueobzGcF
Product

arginine/phenylalanine/histidine-modified generation 5 polyamidoamine dendrimer/EGFP plasmid DNA complex nanoparticles

Diameter: ~ 65 nm

Hydrodynamic diameter: ~ 120 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
  1. ZOuDiBBsMW4r6yck
  2. cSnuky
Product

arginine/phenylalanine/histidine-modified generation 5 polyamidoamine dendrimer/EGFP plasmid DNA complex nanoparticles

Hydrodynamic diameter: ~ 227 nm

Medium: water

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  1. T6jtUgMQCRw3Zkmo
  2. ivQgCs
Product

arginine/phenylalanine/histidine-modified generation 5 polyamidoamine dendrimer/EGFP plasmid DNA complex nanoparticles

Hydrodynamic diameter: ~ 236 nm

Medium: water

Support: none

Method 4

Type: Chemical synthesis
Source:
  1. iFsBPdEe9F8s4ikJ
  2. 47qdoe
Product

arginine/phenylalanine/histidine-modified generation 5 polyamidoamine dendrimer/EGFP plasmid DNA complex nanoparticles

Hydrodynamic diameter: ~ 188 nm

Medium: water

Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  1. ko5CGQpeoueq4AKT
  2. gJ1F34
Product

arginine/phenylalanine/histidine-modified generation 5 polyamidoamine dendrimer/EGFP plasmid DNA complex nanoparticles

Hydrodynamic diameter: ~ 200 nm

Medium: water

Support: none

References

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