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bicontinuous cubic liquid crystalline nanoparticles

Based on

33 Articles
2018 Most recent source

Composition

1

hyaluronic acid-hydrazinated poly(aspartic acid) conjugate

HA-hyd-PASP conjugate HA-PASP
Type Biomolecule
Formula
Role carriers
2

doxorubicin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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drug release dependent on pH
Zeta potential

Applications

Area Application Nanomaterial Variant Source
drug delivery

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medicine/veterinary

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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scanning electron microscopy
transmission electron microscopy
UV
UV-Vis spectroscopy

Biological effects

Biological system Test details Nanomaterial Variant Source
7-week-old male BALB/c, nu/nu mouse bearing human hepatic adenocarcinoma (SK-HEP-1) xenograft

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • zinc nitrate hexahydrate
  • doxorubicin
  1. dfxTnVWP8HhsVUqSSNyRnMTCm
Product

bicontinuous cubic liquid crystalline nanoparticles

Hydrodynamic diameter: ~ 95 - ~ 150 nm

Size: 40 - 70 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • doxorubicin
  • chitosan-stearic acid conjugate
  1. O6u7t
Product

bicontinuous cubic liquid crystalline nanoparticles

Hydrodynamic diameter: 32.2 - 37.0 nm

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • doxorubicin
  • lithocholic acid-poly(ethylene glycol)-lactobionic acid
  1. JTJtJE94aNHjq
Product

bicontinuous cubic liquid crystalline nanoparticles

Hydrodynamic diameter: 650.9 - 1082.3 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • doxorubicin
  • lithocholic acid-poly(ethylene glycol)-lactobionic acid
  1. lB4HG7BsAbTvF
Product

bicontinuous cubic liquid crystalline nanoparticles

Hydrodynamic diameter: 779.8 - 1052.0 nm

Medium/Support: none

Method 5

Type: Physical formation
Source:
  1. A4bWZ7
Product

bicontinuous cubic liquid crystalline nanoparticles

Hydrodynamic diameter: ~ 100 nm

Medium: phosphate buffer solution

Support: none

References

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