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camptothecin/curcumin-loaded polymeric nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

poly(vinyl alcohol)

polyvinyl alcohol PVOH PVAI PVA
Type Polymer
Formula
Role layer
3

chitosan

Type Biomolecule
Formula
Role layer
4

(S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione

1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione (S)-(+)-camptothecin camptothecin CPT CMT CP
Type Single Compound
Formula C20H16N2O4
Role loaded material
5

(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione

(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione 1,7-bis(4-hydroxy-3-methoxy phenyl)-1,6-heptadiene-3,5-diene 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione keto form curcumin diferuloylmethane curcumin CCM CUM CUR Cum Cur CM CU Cm
Type Single Compound
Formula C21H20O6
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • (S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
  • poly(lactic-co-glycolic acid)
  • (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
  1. Tz5p14Mju7gZcQgFhsBndTIGC5k9WY6xn4r8HrW7XyYG
Product

camptothecin/curcumin-loaded polymeric nanoparticles

Hydrodynamic diameter: ~ 266 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • (S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
  • poly(lactic-co-glycolic acid)
  • (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
  1. JqKoXKyVl9Wq0Sc6xPvmyQws2J8Z5sKKb2z2ebgbbDMC
Product

camptothecin/curcumin-loaded polymeric nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • (S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
  • poly(lactic-co-glycolic acid)
  • (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
  1. zUfwkcpuwkKhbpl8WJILfYVQQSJs84G7FDdTSUUyusVh
Product

camptothecin/curcumin-loaded polymeric nanoparticles

Size: not specified

Medium/Support: none

References

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